Detection and development of a quantitation method for undeclared compounds in antidiabetic biologically active additives and its validation by high performance liquid chromatography

A Novel High-Performance Liquid Chromatography Method for Detection of Alginate in Pseudomonas aeruginosa

Background and Objective: The opportunistic pathogen Pseudomonas aeruginosa secrets a capsule-like polysaccharide called alginate which is important for evasion of host defenses, especially in patients with suppressed immunity. Method of alginate determination has an important role in the study of microb...

Method Development and Validation of Carisoprodol and its Impurities by Ultra Violet-High Performance Liquid Chromatography

Ultraviolet-h igh performance liquid chromatographic (UV-HPLC) method was developed for the quantitation of carisoprodol and its impurities viz 2-methyl-2-propylpropane-1, 3-diyl d icarbamate (impurity-D) and N-isopropyl -2-methyl-2-propyl-3-hydroxy propyl carbamate (impurity-B) in active pharmaceutical ingredient. Validation of the method showed excellent sensitivity, selectivity, accuracy, pr...

A quick and easy high performance liquid chromatography method for evaluation of cefixime in human plasma

Cefixime is essential member of orally energetic third generation cephalosporin and has tremendous activity aligned with many pathogens. The virtual bioavailability of a newly industrial dispersible tablet as compared with a recognized identified formulation.  A simple and available reversed-phase HPLC method with UV detection has been urbanized and validate for cefixime evaluate in human p...

development and validation of high performance liquid chromatography for determination of nystatin in pharmaceutical formulations

development and validation of a new method for determination of topiramate in bulk and pharmaceutical formulation using high performance liquid chromatography-uv detection after pre-column derivatization

in published high performance liquid chromatographic (hplc) methods for analysis of topiramate (tpm) in pharmaceutical dosage forms and raw materials refractive index detector (rid) has been used which is not available in many laboratories and has low sensitivity. we described a new, sensitive and simple hplc method for determination of topiramate in pharmaceutical forms and in-virto dissolutio...